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| TOR - John McDonald: Placed on 15-Day DL, (Sprained right ankle) | | TOR - David Eckstein: Placed on 15-Day DL, (Sore right hip Flexor) | | SD - Shawn Estes: Purchased From Minors | | HOU - Stephen Randolph: Traded From, Houston (for player to be named) | | ATL - Brayan Pena: Placed on 15-Day DL, (Back strain) |
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| MIN - Scott Baker: Placed on 15-Day DL, (Reaggravated strained right groin) | | COL - Alberto Arias: Purchased From Minors |
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| CLE - Jason Michaels: Designated for Assignment |
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| DET - Matt Joyce: Purchased From Minors | | DET - Jacque Jones: Designated for Assignment | | ATL - Martin Prado: Placed on 15-Day DL, (Sprained left thumb) |
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| STL - Anthony Reyes: Sent to Minors | | PIT - Evan Meek: Designated for Assignment | | NYY - Ian Kennedy: Sent to Minors | | LAA - Dustin Moseley: Placed on 15-Day DL, (Forearm stiffness) | | ATL - Julio Franco: Retired |
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| DET - Freddy Dolsi: Purchased From Minors | | DET - Denny Bautista: Placed on 15-Day DL, (Right shoulder tendinitis) | | CHC - Rich Hill: Sent to Minors |
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